Inter-individual variation in Range Accessories facial shape is one of the most noticeable phenotypes in humans, and it is clearly under genetic regulation; however, almost nothing is known about the genetic basis of normal human facial morphology.We therefore conducted a genome-wide association study for facial shape phenotypes in multiple discove
SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function
Abstract Modelling insulin-glucose homeostasis may provide novel functional insights.In particular, simple models are clinically useful if they yield diagnostic methods.Examples include the homeostasis model assessment (HOMA) and the quantitative insulin sensitivity check index (QUICKI).However, limitations of these approaches have been criticised.
Comparison of lateral parapatellar vs. infrapatellar approaches for intramedullary nailing for tibial shaft fractures
BackgroundThis study aimed to evaluate the clinical and functional outcomes of tibial shaft fractures treated with intramedullary nailing (IMN) using the lateral parapatellar entry (LPE) and infrapatellar Interior Door Handles (IP) surgical approaches.MethodsA total of 85 patients with tibial shaft fractures treated with IMN between January 2019 an
Calorie restriction during gestation impacts maternal and offspring fecal microbiome in mice
BackgroundMaternal undernutrition is the most common cause of fetal growth restriction (FGR) worldwide.FGR increases morbidity and mortality during infancy, as well as contributes to adult-onset diseases including obesity and type 2 diabetes.The role of the maternal or offspring microbiome in growth outcomes following FGR is not well understood.Met